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| Place of Origin: | China |
| Brand Name: | Phytocare |
| Minimum Order Quantity: | Negotiation |
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| Price: | Negotiation |
| Packaging Details: | 100g/tin, 1kg/tin, 25kg/drum |
| Payment Terms: | L/C, D/A, D/P, T/T,PAYPAL |
| Supply Ability: | 2000kg/month |
| Product: | Vitamin B12 | Other Name: | Cyanocobalamin (Cobalamin) |
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| CAS No.: | 68-19-9 | Purity: | 97.0-102.0% |
| Appearance: | Dark Red Crystals Or Dark Red Crystalline | Functions: | Dementia And Cognitive Function, Cardiovascular Diseases |
| Highlight: | weight loss supplements,natural energy supplements |
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Natural Dietary Supplements VitaminB12 (Cyanocobalamin) (Cobalamin) for Dementia and cognitive function
Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. Vitamin B12 exists in several forms and contains the mineral cobalt, so compounds with vitamin B12 activity are collectively called “cobalamins”. Methylcobalamin and 5-deoxyadenosylcobalamin are the forms of vitamin B12 that are active in human metabolism.
Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine. Methionine is required for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 different substrates, including DNA, RNA, hormones, proteins, and lipids. L-methylmalonyl-CoA mutase converts L-methylmalonyl-CoA to succinyl-CoA in the degradation of propionate an essential biochemical reaction in fat and protein metabolism. Succinyl-CoA is also required for hemoglobin synthesis.
Vitamin B12, bound to protein in food, is released by the activity of hydrochloric acid and gastric protease in the stomach. When synthetic vitamin B12 is added to fortified foods and dietary supplements, it is already in free form and, thus, does not require this separation step. Free vitamin B12 then combines with intrinsic factor, a glycoprotein secreted by the stomach’s parietal cells, and the resulting complex undergoes absorption within the distal ileum by receptor-mediated endocytosis. Approximately 56% of a 1 mcg oral dose of vitamin B12 is absorbed, but absorption decreases drastically when the capacity of intrinsic factor is exceeded (at 1–2 mcg of vitamin B12).
Benefits & Applications:
Pharmaceuticals
Dietary Supplements
Treatment of Cardiovascular diseases
Dementia and cognitive function
Certificate of Analysis:
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Product Name: Cyanocobalamin (Vitamin B12) Batch No.: C200707 MFG: July 08, 2020 Expiry Date: July 07, 2025 Report on: July 19, 2020 Quantity: 100kg |
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| Items | Standards | Test Result |
| Characters | Dark red crystals or dark red crystalline | Complies |
| Identification A | UV: Absorption maxima at 278±1nm,361±1nm and 550±2nm | Complies |
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A361nm/A278nm: 1.70-1.90 A361nm/A550nm: 3.15-3.45 |
1.85 3.27 |
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| Identification B | TLC: The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution | Complies |
| Loss on drying | ≤10.0% | 3.7% |
| Assay | 97.0%-102.0% | 98.9% |
| Related substances | Total impurities ≤3.0% | 0.7% |
| The total aerobic microbial count | ≤1000 cfu/g | <10 cfu/g |
| The total combines yeasts/mold count | ≤100 cfu/g | <10 cfu/g |
| Purity (HPLC) | ≥98.0% | 98.5% |
| Conclusion |
QUALIFIED Complies with the specification of EP9.0, BP2018 |
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Natural Plant Extracts for Dietary Supplements
| Plant Source | Active Ingredient | CAS No. | Popular Specifications |
| Magnolia Bark Extract | Magnolol | 528-43-8 | 90%, 95%, 98% |
| Magnolia Bark Extract | Honokiol | 35354-74-6 | 90%, 95%, 98% |
| Mango Leaf Extract | Mangiferin | 4773-96-0 | 90%, 95% |
| Marigold Flower Extract | Lutein | 127-40-2 | 5% Extract Powder |
| Marigold Flower Extract | Lutein | 127-40-2 | 5% CWS Powder |
| Marigold Flower Extract | Lutein | 127-40-2 | 10% Esters Beadlets GF |
| Marigold Flower Extract | Lutein | 127-40-2 | Easter 5% CWS Powder |
| Marigold Flower Extract | Lutein | 127-40-2 | 20% Oil Suspension |
| Milk Thistle Seed Extract | Silymarin | 65666-07-1 | 60%, 80%, DAB, EP |
| Milk Thistle Seed Extract | Silymarin + Silybin | 22888-70-6 | 90%, 95%, 98% |
| Milk Thistle Seed Extract | Silybin | 65666-07-1 + 22888-70-6 | 80% UV: Silybin 30%, 35% |
| Persimmon Leaf Extract | Ursolic acid | 77-52-1 | 10%, 50%, 90%, 98% |
| Polygonum Cuspidatum Extract | Resveratrol | 501-36-0 | 50%, 98%, 99% |
| Soap Nut Extract | Saponins | 223748-41-2 | 70% |
| Sophora Japonia Extract | Rutin | 153-18-4 | NF11, DAB, EP |
| St. John wort Extract | Hypericin | 548-04-9 | 0.3% |
| White Peony Extract | Paeoniflorin | 23180-57-6 | 10%, 20%, 50% |
| White Willow Extract | Salicin | 138-52-3 | 10%, 15%, 98% |
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